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عمومی::
مفناید استات
Topical antibiotic salves include 11% mafenide acetate (Sulfa- mylon), 1% silver sulfadiazine (Silvadene), polymyxin B, neomy- cin, bacitracin, mupirocin, and the antifungal agent nystatin.
Mafenide acetate (Sulfamylon) Broad-spectrum antimicrobial; penetrates eschar; may cause pain in sensate skin; wide application may cause metabolic acidosis; mild inhibition of epithelialization
Nystatin (Mycostatin) Effective in inhibiting most fungal growth; cannot be used in combination with mafenide acetate Mupirocin (Bactroban) More effective staphylococcal coverage; does not inhibit epithelialization; expensive
0.5% Silver nitrate Effective against all microorganisms; stains contacted areas; leaches sodium from wounds; may cause methemoglobinemia 5% Mafenide acetate Wide antibacterial coverage; no fungal coverage; painful on application to sensate wound; wide application associated
Mafenide acetate is another topical agent with a broad spec- trum of activity because of its sulfa moiety.
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